7.EVALUATION OF HYPOGLYCEMIC POTENTIAL OF THREE ETHNO-HERBS IN STREPTOZOTOCIN – INDUCED DIABETIC RATS By ASHA ARORA_ VINITA PALIWAL AND JAYSHREE JOURWAL

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  • ASHA ARORA, VINITA PALIWAL AND JAYSHREE JOURWAL

Abstract

Catharanthus roseus (L.) G. Don (Apocyanaceae), Momordica charantia L. (Cucurbitaceae) and Syzygium cumini (L) Skeels (Myrtaceae) has been documented as an ethno-hypoglycemic herbs from south-east Rajasthan. Therefore, to evaluate their potential an oral administration of the aqueous extract was administered for 15 days at the concentration of 500 mg /kg body weight in STZ induced hyperglycemic activity. GBC was used in another group to support the results at the concentration of 0.25 mg /kg body weight orally once a day for 15 days. Hypoglycemic activity was observed in all the treated groups revealing significant reduction in blood glucose levels. The results were also found akin to urino-analysis and the body weight tendencies. The performance of Catharanthus roseus was found better as compared to other two and is quite comparable with GBC. Results indicate presence of insulin mimicking natural products in all 3 plants which may contribute for the exploration of new safer drugs.
KEY WORD: Diabetes mellitus, streptozotocin (STZ), Glibenclamide,
Catharanthus roseus, Momordica charantia, Syzygium cumini.

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Author Biography

ASHA ARORA, VINITA PALIWAL AND JAYSHREE JOURWAL

EVALUATION OF HYPOGLYCEMIC POTENTIAL OF
THREE ETHNO-HERBS IN STREPTOZOTOCIN –
INDUCED DIABETIC RATS
ASHA ARORA, VINITA PALIWAL AND JAYSHREE JOURWAL
DEPARTMENT OF BIOTECHNOLOGY, B.N.P.G. COLLEGE,
UDAIPUR, (RAJ.) INDIA.
ashararora@gmail.com , araudr@gmail.com

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Published

2013-06-01

How to Cite

AND JAYSHREE JOURWAL, A. A. V. P. (2013). 7.EVALUATION OF HYPOGLYCEMIC POTENTIAL OF THREE ETHNO-HERBS IN STREPTOZOTOCIN – INDUCED DIABETIC RATS By ASHA ARORA_ VINITA PALIWAL AND JAYSHREE JOURWAL. LIFE SCIENCES LEAFLETS, 40, 49 to 54. Retrieved from https://petsd.org/ojs/index.php/lifesciencesleaflets/article/view/543

Issue

Vol. 40 (2013): JUNE, 2013.....ISSN 0976 - 1098(On Line) ISSN 2277 - 4297(Print)

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Articles

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