Environmental friendly Synthesis of 1-(2-amino-5-(2, 3, 4-substitutedphenyl)thiazol-4-yl)ethan-1-one under aqueous condition

Authors

  • Dasharath Chavhan Indira Mahavidyalaya, kalamb Dist. Yavatmal
  • Sonparote 1Department of Chemistry, B.B. Arts, N.B. Commerce and B.P. Science College Digras, Dist. Yavatmal(M.S.) India
  • Pawar

Abstract

Abstract

Environmentally benign low cost synthesis of some biologically important derivatives of 1-(2-amino-5-(2,3,4-substitutedphenyl)thiazol-4-yl)ethan-1-one (4) by mechanochemical methods were carried out using the naturally obtained CaO as a base catalyst from 2-bromo-1-(2,4-dichlorophenyl)but-3-yn-1-one (1) and substituted Thioureas. The reactions were performed in the aqueous medium. The structures of all synthesized compounds were established on the basis of elemental analysis, IR, NMR and Mass spectral data.

Keywords

Environmentally benign, low cost, naturally obtained base catalyst, aqueous medium, CaO

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Published

2023-10-10

How to Cite

Chavhan, D., Sonparote, P., & Pawar, M. (2023). Environmental friendly Synthesis of 1-(2-amino-5-(2, 3, 4-substitutedphenyl)thiazol-4-yl)ethan-1-one under aqueous condition. INTERNATIONAL RESEARCH JOURNAL OF CHEMISTRY, 40. Retrieved from https://petsd.org/ojs/index.php/irjc/article/view/1723