2. SYNTHESIS OF COUMARINS AND INVESTIGATION OF THEIR ANTIMICROBIAL ACTIVITY by PAVANKUMAR MURALAKAR AND SURESHA KUMARA T. H.

Authors

  • PAVANKUMAR MURALAKAR AND SURESHA KUMARA T. H.

Abstract

A laboratory experiment was conducted in Dept. of Chemistry, Kuvempu University, Shankaraghatta, Karnataka, India to synthesize coumarins and investigate their antimicrobial activity during 2007-08. 3.5 g yield of 4-Methyl-benzocoumarin was obtained with the 48.01 per cent yield, 110 ?C melting point and 0.813 Rf value (Retention factor value). The derivatives 4-methyl-7-nitrobenzocoumarin and 3-bromo-4-methyl-7-nitro benzocoumarin were also prepared in the laboratory which yielded 2 g and 0.6 g respectively. The antibacterial activity of 4-Methyl-benzocoumarin and its derivatives on micro-organisms i.e. Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa was found positive.
KEYWORDS: Coumarins, Antimicrobial activity

Downloads

Download data is not yet available.

Author Biography

PAVANKUMAR MURALAKAR AND SURESHA KUMARA T. H.

SYNTHESIS OF COUMARINS AND INVESTIGATION OF THEIR ANTIMICROBIAL ACTIVITY
PAVANKUMAR MURALAKAR AND
SURESHA KUMARA T. H. 
DEPARTMENT OF CHEMISTRY, KUVEMPU UNIVERSITY, SHANKARAGHATTA, KARNATAKA.
Corresponding author email: pkmuralkar@gmail.com

Downloads

Published

2017-04-01

How to Cite

AND SURESHA KUMARA T. H., P. M. (2017). 2. SYNTHESIS OF COUMARINS AND INVESTIGATION OF THEIR ANTIMICROBIAL ACTIVITY by PAVANKUMAR MURALAKAR AND SURESHA KUMARA T. H. INTERNATIONAL RESEARCH JOURNAL OF CHEMISTRY, 17, 16 to 26. Retrieved from https://petsd.org/ojs/index.php/irjc/article/view/112

Issue

Vol. 17 (2017): VOL. 17 PUBLISHED ON 1ST APRIL 2017 (QUATERLY PUBLISHED)

Section

Research Paper

License

Copyright Notice

Authors retain all their rights to the published works, such as (but not limited to) the following rights;

  • Copyright and other proprietary rights relating to the article, such as patent rights,
  • The right to use the substance of the article in own future works, including lectures and books,
  • The right to reproduce the article for own purposes,
  • The right to self-archive the article 
  • The right to enter into separate, additional contractual arrangements for the non-exclusive distribution of the article's published version (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal (IRJC).