Proteinase inhibitors (PIs) are naturally occurring proteins in living organisms and are able to inhibit & control the activity of proteases. PIs are a diverse group of proteins that share a common biochemical activity. The role of plant proteinase inhibitors was investigated by Mickel and Standish in 1947 when they observed the insects larvae were unable to develop normally on soybean products. Subsequently, the soybean trypsin inhibitors were found to be lethal to the flour beetle larvae, Tribolium confusum (Lipke et. al., 1954). Now there are diverse examples of protease inhibitors active against many insect species both in vitro (Pannetier et. al., 1997; Koiwa et. al., 1998) and in vivo (Urwin et. al., 1997; Vain et. al., 1998) bioassays.

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How to Cite
N.J.CHIKHALE2, R.S.DHANDE1. PLANT PROTEASE INHIBITORS: STRATEGY FOR PEST CONTROL IN CROPS. LIFE SCIENCES LEAFLETS, [S.l.], v. 58, nov. 2014. ISSN 0976-1098. Available at: <>. Date accessed: 16 aug. 2017.