2. ANTIMICROBIAL ACTIVITY OF LEAF EXTRACTS OF PELTOPHORUM PTEROCARPUM (DC)-AN IN-VITRO STUDY by JENI R. PATEL1 AND DR. T. G. GOHIL2
The antibacterial activity of crude extract of leaves of Peltophorum pterocarpum belonging to family Caesalpiniaceae, was evaluated in-vitro against some selected clinical isolates including Escherichia coli, Pseudomonas aeruginosa, Klebsiella spp, Proteus vulgaris, Proteus mirabilis Staphylococcus aureus and Candida albicans by disc diffusion and agar-well diffusion method. Two solvents chloroform and methanol were used for extraction of bioactive constituents from fresh leaves by maceration technique. The yield (%) of crude extract was 2.8 and 4.88 respectively. The potency of crude extract was determined by measuring diameter of zone of inhibition. It was concluded from the results that methanolic as well as chloroform extracts of Peltophorum pterocarpum were significant effect against the all clinical isolates which are serious human pathogen causing UTI and wound infections. Therefore, the leaf extracts of this plant can be selected for further investigation to determine their therapeutic potential.
KEY WORD: Antimicrobial, Crude extract, Clinical isolates, Zone of inhibition, UTI.