SYNTHESIS, CHARACTERISATION AND ANTIMICROBIAL STUDIES OF CHALCONES

  • 1P. R. DESAI AND 2S. D. DESAI

Abstract

Title chalcones have been prepared by reaction of 1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone and various benzaldehyde  to give 1-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(substitutedphenyl)prop-2-en-1-one (1 a-i).

The structural assignment of the compounds was based on elements analysis and IR, 1H NMR and Mass spectral data. All the synthesized compounds have been screened for their antimicrobial activity to gram-positive and gram-negative bacterial strains and antifungal activity. The antimicrobial activities of the synthesized compounds have been compared with standard drugs like Amoxycillin, Ciprofloxecine and Griseofulvin. Purity of synthesized compounds has been checked by TLC.

How to Cite
2S. D. DESAI, 1P. R. DESAI AND. SYNTHESIS, CHARACTERISATION AND ANTIMICROBIAL STUDIES OF CHALCONES. INTERNATIONAL RESEARCH JOURNAL OF CHEMISTRY, India, v. 4, dec. 2013. ISSN 2321-2845. Available at: <http://petsd.org/ojs/index.php/irjc/article/view/19>. Date accessed: 21 sep. 2017.
Section
RESEARCH PAPER