IN VITRO EVALUATION OF ANTIFUNGAL ACTIVITY OF COMBINATION OF METHANOL EXTRACT OF TEMINALIA CHEBULA FRUIT AND AMPHOTERICIN B AGAINST CANDIDA ALBICANS

  • 1. P. J. VYAS, 1. A. S. SUTHAR AND 2. A. D. PATEL 1. DEPARTMENT OF CHEMISTRY, SHETH M.N.SCIENCE COLLEGE, PATAN, GUJARAT, INDIA. 2. M. N. COLLEGE, VISNAGAR. Email: vyaspiyushj@yahoo.com

Abstract

Terminalia chebula Retz. belongs to the family “Combretaceae”, is a valuable medicinal plant . T. chebula showed a number of medicinal activities due to the presence of a large number of different types of phytochemicals. Amphotericin B  is a very useful antibiotic for fungal infections. This present study has been done to evaluate the interaction between methanol extract of the fruits of T. chebula and Amphotericin B on their antifungal activity against Candida albicans. The results of this study showed that there is an increased activity in case of combination of plant extract and antibiotic. This Combination therapy could be a new way to treat diseases which are caused by Candida albicans (MTCC 183).

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How to Cite
2. A. D. PATEL, 1. P. J. VYAS, 1. A. S. SUTHAR AND. IN VITRO EVALUATION OF ANTIFUNGAL ACTIVITY OF COMBINATION OF METHANOL EXTRACT OF TEMINALIA CHEBULA FRUIT AND AMPHOTERICIN B AGAINST CANDIDA ALBICANS. INTERNATIONAL RESEARCH JOURNAL OF CHEMISTRY, India, v. 6, june 2014. ISSN 2321-2845. Available at: <http://petsd.org/ojs/index.php/irjc/article/view/124>. Date accessed: 20 oct. 2017.
Section
RESEARCH PAPER

Keywords

Terminalia chebula, Amphotericin B, Candida albicans, Combination therapy.